Doxapram (DX) for apnea (A) of prematurity; effects on pulmonary function
نویسندگان
چکیده
منابع مشابه
Doxapram Treatment for Apnea of Prematurity: A Systematic Review.
BACKGROUND Apnea of prematurity (AOP) is a common complication of preterm birth, for which caffeine is the first treatment of choice. In case of persistent AOP, doxapram has been advocated as an additional therapy. OBJECTIVE To identify and appraise all existing evidence regarding efficacy and safety of doxapram use for AOP in infants born before 34 weeks of gestational age. METHODS All stu...
متن کاملLong-Term Neurodevelopmental Outcome after Doxapram for Apnea of Prematurity.
BACKGROUND Doxapram has been advocated as a treatment for persistent apnea of prematurity (AOP). OBJECTIVE To evaluate the effect of doxapram on long-term neurodevelopmental outcome in preterm infants as its safety still needs to be established. METHODS From a retrospective cohort of preterm infants with a gestational age (GA) <30 weeks and/or a birth weight <1,250 g, born between 2000 and ...
متن کاملEffect of Caffeine and Aminophylline on Apnea of Prematurity
Background: The most common type of apnea among premature newborns is idiopathic apnea of prematurity. Recurrent apnea can lead to hypoxemia and central nervous system damage. Although caffeine and theophylline are the most commonly prescribed drugs in this field, there is disagreement about which medicine is preferred. The purpose of this study was to compare the ther...
متن کاملEffects of doxapram on postoperative pulmonary complications following thoracotomy.
An i.v. solution of 5% dextrose with doxapram 2 mg ml-1 or 5% dextrose alone was administered to 53 patients following lateral thoracotomy. Estimations of arterial PO2, PCO2 and pH were made before operation, during infusion and 7 days after after operation. Respiratory function tests were carried out before and 7 days after operation. There were no significant differences in arterial PO2, PCO2...
متن کاملDoxapram Use for Apnoea of Prematurity in Neonatal Intensive Care
Apnoea of prematurity is treated with noninvasive respiratory therapy and methylxanthines. For therapy unresponsive apnoea doxapram is often prescibed in preterm neonates. The duration, dosage and route of administration of doxapram together with its efficacy was evaluated in two Dutch neonatal intensive care. Outcome concerning short-term safety and neonatal morbidity were evaluated. During 5 ...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1987
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-198708000-00103